USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: SH3L1_HUMAN USC-OGP 2-DE database:  SH3L1_HUMAN SH3L1_HUMAN General information about the entry View entry in simple text format Entry name SH3L1_HUMAN Primary accession number O75368 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;. Gene name Name=SH3BGRL Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0597: pI=5.17; Mw=12454 SPOT OGP-0599: pI=5.19; Mw=12269 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0855: pI=5.18; Mw=13405 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1337: pI=5.29; Mw=15865 SPOT OGP-1345: pI=5.27; Mw=14950 Cross-references UniProtKB/Swiss-Prot O75368; SH3L1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SH3L1_HUMAN Primary accession number O75368 Secondary accession number(s) Q3SYL1 Q5JT50 Q6FIE8 Q9H0N8 Sequence was last modified on  November 1, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 146) Name and origin of the protein Description RecName: Full=SH3 domain-binding glutamic acid-rich-like protein; Gene name Name=SH3BGRL Encoded on Name=SH3BGRL Keywords 3D-structure; Complete proteome; Reference proteome; SH3-binding. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF042081; AAC27445.1; -; mRNA EMBL AL136718; CAB66652.1; -; mRNA EMBL CR533478; CAG38509.1; -; mRNA EMBL AL357115; CAI39436.1; -; Genomic_DNA EMBL BC016709; AAH16709.1; -; mRNA EMBL BC103762; AAI03763.1; -; mRNA CCDS CCDS14449.1; -; . PIR JE0178; JE0178; . RefSeq NP_003013.1; NM_003022.2; . UniGene Hs.108029; -; . PDB 1U6T; X-ray; 1.90 A; A=2-114 PDB 1WRY; NMR; -; A=1-108 PDBsum 1U6T; -; . PDBsum 1WRY; -; . ProteinModelPortal O75368; -; . SMR O75368; -; . BioGrid 112349; 15; . IntAct O75368; 2; . MINT MINT-1562247; -; . STRING 9606.ENSP00000362308; -; . iPTMnet O75368; -; . PhosphoSitePlus O75368; -; . BioMuta SH3BGRL; -; . DOSAC-COBS-2DPAGE O75368; -; . OGP O75368; -; . REPRODUCTION-2DPAGE O75368; -; . SWISS-2DPAGE O75368; -; . EPD O75368; -; . PaxDb O75368; -; . PeptideAtlas O75368; -; . PRIDE O75368; -; . TopDownProteomics O75368; -; . Ensembl ENST00000373212; ENSP00000362308; ENSG00000131171; . GeneID 6451; -; . KEGG hsa:6451; -; . CTD 6451; -; . DisGeNET 6451; -; . GeneCards SH3BGRL; -; . HGNC HGNC:10823; SH3BGRL; . HPA HPA051248; -; . MIM 300190; gene; . neXtProt NX_O75368; -; . OpenTargets ENSG00000131171; -; . PharmGKB PA35731; -; . eggNOG KOG4023; Eukaryota; . eggNOG ENOG4111N7M; LUCA; . GeneTree ENSGT00440000039098; -; . HOGENOM HOG000095212; -; . HOVERGEN HBG054781; -; . InParanoid O75368; -; . OMA EEKYCGN; -; . OrthoDB EOG091G10PC; -; . PhylomeDB O75368; -; . TreeFam TF105574; -; . ChiTaRS SH3BGRL; human; . EvolutionaryTrace O75368; -; . GeneWiki SH3BGRL; -; . GenomeRNAi 6451; -; . PRO PR:O75368; -; . Proteomes UP000005640; Chromosome X; . Bgee ENSG00000131171; -; . CleanEx HS_SH3BGRL; -; . ExpressionAtlas O75368; baseline and differential; . Genevisible O75368; HS; . GO GO:0005737; C:cytoplasm; TAS:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0005634; C:nucleus; TAS:UniProtKB; . GO GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc; . Gene3D 3.40.30.10; -; 1; . InterPro IPR006993; Glut_rich_SH3-bd; . InterPro IPR012336; Thioredoxin-like_fold; . Pfam PF04908; SH3BGR; 1; . PIRSF PIRSF008142; SH3-bind_E-rich_L; 1; . SUPFAM SSF52833; SSF52833; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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